How to Take Viagra ?

Viagra is an oral medication that comes in pill form. In the U.S., it’s prescribed as needed to men with ED.

As-needed Viagra is taken before sex, so you’ll need to do some planning. Be sure to take Viagra one hour (but no more than four hours) before you plan to engage in sexual activity.

Also, you can take it on an empty stomach or with food, though if you’re hitting up a burger joint, know it may take Viagra longer to kick in when taken with fatty foods. For more tips, check out our blog on how to take sildenafil citrate (Viagra).

When you filled your prescription, the pharmacist probably gave you a quick rundown of the basics, which probably included a fair amount of confusing medical jargon. We’re here to break it down for you, so you know exactly how to take sildenafil for erectile dysfunction.

To start, there are typically three dose strengths of sildenafil that healthcare providers will prescribe, based on your needs — 25mg, 50mg and 100mg. For most patients, the recommended dose of sildenafil is 50mg taken as needed, approximately one hour before sexual stimulation. Hims now offers a sildenafil chew at different dosages allowing you to take sildenafil as-needed to suit your sex life.

Based on the effectiveness and ability to tolerate the drug, your healthcare professional may adjust the dosage up to 100mg or down to 25mg.

It is important to note here that the maximum dose per day is 100mg of sildenafil, so don’t take another 100mg if the first isn’t working the way it should.

How to Take Sildenafil With Food

Before popping that little blue pill, there are a few things you should know.

Sildenafil does not protect you from STIs. Therefore, you should always practice safe sex and wear a condom.

You can take sildenafil with food or on an empty stomach. However, avoid high-fat foods, high-fat meal can block the absorption of sildenafil citrate and can make the drug less effective for your erection.

If you do plan to eat a meal before taking sildenafil, make sure to have it as your breakfast or lunch. That way, it gives your body time to digest the food, making it quick and easier for sildenafil to absorb into the bloodstream.

Grapefruit juice may also impede or delay the absorption of sildenafil in the body. Make sure to seek medical advice from a healthcare provider about eating grapefruit and drinking grapefruit juice while taking sildenafil.

How Viagra® Works ?

Millions of men use the brand name medication Viagra® every year, making it the single-most popular medication used to treat erectile dysfunction in the country.

And we can see why — it works. Used at the proper dose, Viagra is considered very effective at helping men achieve and maintain an erection and is approved by the Food and Drug Administration for the treatment of ED.

It’s also not a bad thing if you can’t exactly explain how it works. Either way, the famous Pfizer little blue pill can help men aged 18 or older affected by ED to get hard and stay hard when aroused, making sexual activity easier and enhancing sexual performance in general.

But we’re pretty into knowing what we’re putting in our bodies, and we bet you are, too.

So if you’re wondering to yourself “how does Viagra work in the body?” let’s dig a little deeper than “pill makes peen go up,” because although Viagra might seem like an on/off switch for your penis, the way the medication works is fairly complex.

How Viagra Works

Let’s just begin with this very obvious starting question: what does Viagra do? Is it something to do with ball bearings? Quarks? String theory?

Sadly, no. It’s a boring old biological reaction.

Viagra works by inhibiting the enzyme that’s responsible for controlling blood flow in and out of your penis when you’re sexually aroused. Viagra inhibits this phosphodiesterase-5 (PDE5) enzyme — which explains Viagra’s (creatively named) classification as a PDE5 inhibitor.

Now, before we get into this in more detail, it’s important to briefly explain how erectile dysfunction happens and the role PDE5 plays in the process.

Erectile dysfunction, or ED, happens when you get aroused but the PDE5 enzyme stops a sufficient amount of the blood you need to get you hard from flowing into the corpora cavernosa.

Phosphodiesterase type 5 plays a normal role in making the penis flaccid after sex, but in men with erectile dysfunction, PDE5 can make getting erect and staying erect during sex difficult (or impossible). PDE5 is, essentially, number one among the causes of ED.

Viagra then, is the treatment for that cause.

  • By inhibiting PDE5, Viagra makes it easier for blood to flow into the blood vessels in your penis, allowing you to get — and stay — hard during sex.
  • It also reduces the risk of blood flowing back out of your penis during sex, meaning you’re less likely than normal to lose your erection.
  • This makes Viagra (as well as similar medications, such as Cialis® and Levitra®) a highly effective treatment for erectile dysfunction in most men.
  • Other erectile dysfunction medications, such as Cialis and Levitra, also work by inhibiting the PDE5 enzyme.
  • These medications differ from Viagra in how long their effects last — Tadalafil (generic Cialis), for example, can provide relief from erectile dysfunction for as long as 36 hours.

By the way, ED can range in severity — you could find it difficult to get fully erect when you’re sexually aroused but still get a moderate erection. If your ED is severe, your penis might stay entirely flaccid even when you’re aroused, making penetrative sex impossible.

Be sure to seek medical advice from a healthcare professional before you take Viagra and discuss any pre-existing health conditions and any over-the-counter or prescription drugs (such as nitrates) you currently are taking, as these may cause an interaction.

How Long Does it Take for Viagra to Work?

If this is your first time taking Viagra, make sure you plan your sexual activities accordingly — it may not work exactly the way you’ve read online.

Depending on where you got your initial information, the internet suggests that a dose of Viagra could work minutes to hours after taking the pill, and to an extent that’s true. But sticking strictly to the FDA guidelines, Viagra typically kicks in about 30 minutes after you take it, and can work for up to four hours thereafter.

That time frame may be affected by food, your weight, whether you find interesting porn or if your partner does that thing where they run their fingers through your hair.

All we can do is point to the window of effect, and remind you that everyone will have a slightly different experience. Oh, and if you’d like to learn more you can read our blog on how long Viagra lasts.

Buy Cialis Candy Online

Tadalafil is a prescription-only active ingredient approved by the FDA for erectile dysfunction. It was popularized by the brand name Cialis and is designed to last longer than Sildenafil.

Cialis (tadalafil) relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take Cialis while also taking Adcirca, unless your doctor tells you to.

Cialis Candy
Cialis Candy

Important information

Do not take Cialis if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as “poppers”. Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

Some medicines can cause unwanted or dangerous effects when used with Cialis. Tell your doctor about all your current medicines, especially riociguat (Adempas).

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Get medical help at once if you have nausea, chest pain, or dizziness during sex.

Stop using Cialis and get emergency medical help if you have sudden vision loss.

Before taking this medicine

You should not take Cialis if you are allergic to tadalafil.

Taking Cialis with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take this medicine if you also use:

  • riociguat (to treat pulmonary arterial hypertension); or
  • a nitrate drug (for chest pain or heart problems) such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as amyl nitrate or nitrite “poppers”.

Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). Avoid nitrate use during this time.

To make sure this Cialis is safe for you, tell your doctor if you have ever had:

  • heart disease or heart rhythm problems;
  • a heart attack or stroke;
  • angina (chest pain), high or low blood pressure;
  • pulmonary hypertension (unless you are taking tadalafil for this);
  • a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart);
  • liver or kidney disease (or if you are on dialysis);
  • vision loss, or retinitis pigmentosa (an inherited condition of the eye);
  • a bleeding disorder;
  • a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
  • a physical deformity of the penis (such as Peyronie’s disease), or an erection lasting longer than 4 hours;
  • a stomach ulcer; or
  • health problems that make sexual activity unsafe.

Sudden vision loss has occurred in a small number of people taking medicines like tadalafil (Viagra or others). Most of these people already had certain eye problems or had high cholesterol, diabetes, coronary artery disease, a history of smoking, or were over 50 years old). It is not clear whether the medicine was the actual cause of vision loss.

Cialis is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether tadalafil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Cialis is not approved for use by anyone younger than 18 years old.

How should I take Cialis?

Cialis is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Cialis can be taken with or without food.

Do not break or split a tablet. Swallow it whole.

For erectile dysfunction, take Cialis just before sexual activity but not more than once per day.

Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor’s instructions.


Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

As Cialis is used as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Cialis?

Drinking alcohol with this medicine can cause side effects.

Grapefruit and grapefruit juice may interact with tadalafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.

Cialis side effects

Get emergency medical help if you have signs of an allergic reaction to Cialis: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop and get medical help at once if you have nausea, chest pain, or dizziness during sex. You could be having a life-threatening side effect.

Stop using this medicine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis);
  • vision changes or sudden vision loss;
  • ringing in your ears or sudden hearing loss; or
  • heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

Common Cialis side effects may include:

  • headache;
  • flushing (warmth, redness, or tingly feeling);
  • nausea, upset stomach;
  • stuffy nose; or
  • muscle pain, back pain, pain in your arms or legs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Cialis?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • medicines to treat erectile dysfunction or pulmonary arterial hypertension;
  • an antibiotic or antifungal medicine;
  • antiviral medicine to treat hepatitis C or HIV/AIDS;
  • drugs to treat high blood pressure or a prostate disorder; or
  • seizure medicine.

This list is not complete. Other drugs may interact with tadalafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Cialis vs Viagra – What’s the difference between them?

Cialis and Viagra are both PDE5 inhibitors used for the treatment of erectile dysfunction (ED). Both only work when a man is sexually aroused. Cialis lasts for around 36 hours compared with only 4 to 5 hours for Viagra. Food does not affect the activity of Cialis, whereas food may decrease the effectiveness of Viagra. Cialis can be used once daily, at a smaller dosage, and is also effective at treating benign prostatic hyperplasia (BPH). Dosage of Cialis may need to be reduced in men with liver or kidney problems and risk of interactions may be higher than with Viagra.

Cialis and Viagra Comparation
Cialis and Viagra Comparation

What ingredients are contained in Cialis or Viagra and how do they work?

Cialis is the brand name for tadalafil and Viagra is the brand name for sildenafil. Both belong to a class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors. PDE5 inhibitors work only in the presence of sexual stimulation, as they rely on the natural release of nitric oxide (NO), a chemical only released during sexual arousal. NO in turn activates other substances to relax the smooth muscle inside the penis to allow the inflow of blood and an erection to occur. PDE5 inhibitors enhance the effect of NO.

Which drug was first approved and which one lasts for longer?

On March 27 th, 1998, Viagra became the first oral pill, and the first PDE5 inhibitor, to be approved by the FDA to treat ED. A generic for Viagra was approved in March 2016  and released in December 2017.

Cialis was first approved for ED on November 21st, 2003. It was the third PDE5 inhibitor to come onto the market (after Levitra [vardenafil]). Cialis has an advantage over Viagra and Levitra in that it lasts for a lot longer – 36 hours, compared with 4-5 hours for Viagra and Levitra. A generic for Cialis was approved in May 2018  and released in September 2018.

How quickly do Cialis and Viagra work and does food have any effect

Cialis generally works within 16 to 45 minutes, and its activity is not affected by food. Viagra generally works within 30 minutes, and its effect may be diminished if taken soon after a high fat meal (which may also delay how fast it works). For this reason, Viagra is best taken on an empty stomach.1,2,7

Effectiveness of all PDE5 inhibitors is similar; although reported effectiveness of Viagra, at 84% is slightly higher than that of Cialis at 81%.7 However, more men prefer Cialis because of its longer duration of effect.

What is the usual dosage of Cialis or Viagra?

Cialis can be taken on an as needed basis, or daily.1Generally, daily dosages are smaller than as needed doses. Typically, Cialis is taken as a 10mg starting dose, prior to sexual activity. The effects of Cialis will last around 36 hours. The dosage may be increased to 20mg if 10mg is ineffective or reduced to 5mg if side effects are intolerable.1

When Cialis is taken for daily use, the recommended initial dosage is 2.5mg once daily, or 5mg for people who also have BPH. Timing of the daily dosage does not matter in people using it solely for ED; however, those with BPH are advised to take it at the same time each day. Do not take more than one dose a day but your doctor may consider an increase in dosage from 2.5 to 5mg if ineffective. Side effects of Cialis include headache and indigestion.

Viagra is taken on an as needed basis, at a dose of 50mg, approximately 1 hour before sexual activity (although can be taken from 30 minutes to 4 hours before). The dose may be increased to 100mg if 50mg is ineffective or decreased to 25mg if side effects are intolerable.2 Viagra should only be taken once a day even though the effects wear off after approximately 4-5 hours. The main side effects are headache, flushing and indigestion.2 Rarely, color perception may be altered with Viagra. This side effect does not happen with Cialis.

Cost of Viagra varies depending on tablet strength but is approximately $24 per tablet for the 50mg strength and $35 for the 100mg strength. Cialis costs approximately $8.50 for the 5mg strength and $28 for the 20mg strength, per tablet.

All PDE5 inhibitors are contraindicated with nitrates. The longer duration of action of Cialis means it is at higher risk for drug interactions, and dosages may need reducing in men with kidney or liver disease. Cialis is not recommended in men who have had a heart attack or stroke within the past 6 months, with either uncontrolled high blood pressure or severely low blood pressure, unstable angina, or other conditions that make sexual activity inadvisable.

How Viagra works ?

  • Viagra is a brand (trade) name for the drug sildenafil. Sildenafil blocks the action of an enzyme known as cGMP-specific phosphodiesterase type-5 (PDE-5). This enzyme breaks down cGMP, a substance that induces smooth muscles to relax. Blocking PDE-5 means increased levels of cGMP within the smooth muscles which promotes muscle relaxation and vasodilation (a widening of blood vessels).
  • High levels of PDE-5 are found in the penis, lungs, and retina. PDE-5 is also found throughout the body within the smooth muscle cells of blood vessels and muscles. Viagra is approved to treat erectile dysfunction (impotence) in men. Another brand of sildenafil (Revatio) is approved to treat high blood pressure associated with pulmonary arterial hypertension (PAH).
  • Viagra belongs to the class of medicines known as PDE-5 inhibitors.

Viagra for Erectile Dysfunction


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Two hours later a similar result and even woke next morning with a very pleasant erection. Can’t wait for next sex session.